刘俊杰

博士后

个人简介：

●博士毕业于京都府立医科大学

●发表学术论文8篇：

1. Junjie Liu, Kazumi Iwata, Kai Zhu, Misaki Matsumoto, Kenjiro Matsumoto,Nozomi, Asaoka, Xueqing Zhang,Masakazu Ibi, Masato Katsuyama, Masato Tsutsui,Shinichi Kato, Chihiro Yabe-Nishimura*,(2020) NOX1/NADPH oxidase in bone marrow-derived cells modulates intestinal barrier function. Front Microbiol. Free Radical Biology & Medicine 2020;147:90-101.（二区TOP期刊，IF：8.101）

2. Masakazu Ibi#, Junjie Liu#, Noriaki Arakawa, Shiho Kitaoka, Ai Kawaji, Ken-ichi Matsuda, Kazumi Iwata,Misaki Matsumoto,XMasato Katsuyama ,Kai Zhu, Satoshi Teramukai, Tomoyuki Furuyashiki,and Chihiro Yabe- Nishimura* (2017) Depressive-like behaviors are regulated by NOX1/ NADPH oxidase by redox modification of NMDA receptor 1.The Journal of Neuroscience. 2017;37(15):4200-4212. （一区，IF：6.709）

3.Junjie Liu, Kaiqing Liu, Shang Wang,Yanyan Lou, Zi’en Zhang, Dongdong Tang, Jing Liu *, Song Wu *, Aifa Tang*. M1-type differentiation was induced for tumor inhibition through precise regulation of artificial macropha- ge BphS/C-di-GMP by far infrared light. 2023, under review.

4.Misaki Matsumoto, Junjie Liu, Kazumi Iwata, Masakazu Ibi, Nozomi Asaoka, Xueqing Zhang, Masato Katsuyama,   Masaya Matsuda, TakeshiNabe, Katrin Schroder, Chihiro Yabe-Nishimura. NOX1/NADPH oxidase is involved in the  LPS-induced exacerbation of collagen-induced arthritis. Japanese Pharmacological Society. 146( 2021) 88-97. （三区，IF：3.578）

5.Han Wang1,2†, Junjie Liu3†,Yanyan Lou3†,Yang Liu4, Jieqing Chen1,2, Xinhui Liao1,2, Xiuming Zhang3,Chengzhi Zhou5, Hongbing Mei1,2*, Aifa Tang6, *. Identification of Hub Genes Related to the Progression of  Bladder Cancer by an Integrated Bioinformatics Analysis. Scientific Reports. 2023, under review. （三区， IF： 4.379）

6.Kai Zhu , Tomoko Kakehi , Misaki Matsumoto , Kazumi Iwata , Masakazu Ibi ,Yoichi Ohshima , Jia Zhang , Junjie Liu , Xiaopeng Wen , Ashraf Taye, Chunyuan Fan ,Masato Katsuyama , Kumar Sharma , Chihiro Yabe- Nishimura * (2015). NADPH oxidase NOX1 is involved in activation of protein kinase C and prematuresenescence in early stage diabetic kidney. Free Radical Biology & Medicine. 2015;83:21-30. （二区TOP期刊，IF：8.101）

7.Misaki Matsumoto, Jia Zhang, Xueqing Zhang, Junjie Liu, Joy X. Jiang, Kanji Yamaguchi, Akiyuki Taruno, Masato Katsuyamae, Kazumi Iwata, Masakazu Ibi, Wenhao Cui, Kuniharu Matsuno, Yoshinori Marunaka,Yoshito Itoh, Natalie J. Torok, and Chihiro Yabe-Nishimura*（2018）. The NOX1 isoform of NADPH oxidase is involved indysfunction of liver sinusoids in nonalcoholic fatty liver disease. Free Radical Biology & Medicine. 2018;115:412-420. （二区TOP期刊，IF：8.101）

8. XiaopengWen, Kazumi Iwata , Keiko Ikuta, Xueqing Zhang, Kai Zhu, Masakazu Ibi,Misaki Matsumoto, Nozomi Asaoka, Junjie Liu, Masato Katsuyama and Chihiro Yabe-Nishimura*（2019）. NOX1/NADPH  oxidase regulates the expression of multidrug resistance- associated protein 1 and maintains intracellular

glutathione levels. The FEBS Journal. 2019;286:678-687.（二区，IF：5.622）

●参与国家级、市重点项目2项：

1.2021年国家自然基金面上项目： circGLS3竞争性结合hnRNPK和USP32下调 c-myc抑制肾癌发生发展 的新机制研 究 。

2.2022年深圳市科创委技术攻关面上项目：一站式智慧医共体平台关键 技 术 研发。

●参与申请国家发明专利1项：一种用于预测肾透明细胞癌的肿瘤标志物，202311437625X ，2023年10月31日。

·熟练操作与分子生物学相关的各种实验，包括：干细胞培养；胚胎干细胞（ES）和多能干细胞（iPS）的培养和定向诱导；细胞或组织蛋白（WB），DNA（PCR）和RNA（rtPCR）的提取及定量；细胞基因敲除，各种细胞、组织染色及蛋白活性检测；各种动物给药方法（皮下、腹腔、静脉、口饲灌胃）。